June 2023 – Our paper “Synergistic effects on mutagenicity of tandem lesions containing 8-oxo-7,8-dihydro-2ʹ-deoxyguanosine or Fapy•dG flanked by a 3ʹ 5-formyl-2ʹ-deoxyuridine in human cells” was published in DNA Repair. This work is in collaboration with Shijun Gao, Haozhe Yang, and Dr. Marc Greenberg of Johns Hopkins University.
June 15, 2023: Jan Henric T. Bacurio successfully defended his dissertation.
May 8, 2023 – Henric, together with his parents, and Dr. Ashis Basu attended the UConn 2023 Graduation Ceremony for Doctorate Students held in Jorgensen Center for the Performing Arts.
April 2023 – Our paper “8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine” was published in Chemical Research in Toxicology. Stephen Stanio and Henric Bacurio headed this project, the paper’s first authors, and are in collaboration with Dr. Greenberg of Johns Hopkins University.
April 14, 2023 – Alessandra Bassani (Major in MCB, Minor in PNB and Italian Literature and Cultural Studies, UConn Class of 2023) presented her project, toxicity and mutagenicity of the bulky DNA-peptide crosslink (DpC) lesion when replicated in bacterial cells, during the 26th annual frontiers: undergraduate research poster exhibition.
March 2023 – A poster session was held during the Open House for prospective students. Srijana and Priscilla presented their findings on oxidative DNA damage and bulky DNA-peptide crosslink (DpC), respectively.
August 2022 – Henric received an “outstanding service and research award” from UConn Chemistry. This award recognizes a Chemistry graduate student for outstanding performance in research and service in the Department of Chemistry.
Stephen Stanio (MCB, UConn Class of 2022) is pursuing a PhD in Biological Sciences at the University of Maryland – College Park.
Our work about “Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication” was published in JACS. This is in collaboration with Dr. Freudenthal of the University of Kansas Medical Center and Dr. Greenberg of Johns Hopkins University.
Stephen Stanio (MCB, UConn Class of 2022) presented his project about the mutagenicity of the oxidative lesion 8-oxodG during the 25th annual Frontiers: Undergraduate research poster exhibition (April 9, 2022).